H Cadherin Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
---|---|
Primary Accession | P55290 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | CDH13; CDHH; H-cadherin; Heart cadherin; P105; T cad; T Cadherin; Truncated cadherin; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 78287 Da |
Dilution | WB 1:500~1:2000 IHC 1:50~1:200 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human H Cadherin |
Description | Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | CDH13 |
---|---|
Synonyms | CDHH |
Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth. |
Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q9WTR5}; Lipid-anchor, GPI-anchor. Cytoplasm {ECO:0000250|UniProtKB:Q9WTR5} |
Tissue Location | Highly expressed in heart. In the CNS, expressed in cerebral cortex, medulla, hippocampus, amygdala, thalamus and substantia nigra. No expression detected in cerebellum or spinal cord |
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