MPP6 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, WB, E |
---|---|
Primary Accession | Q9NZW5 |
Other Accession | Q9JLB0 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 61117 Da |
Antigen Region | 360-388 aa |
Gene ID | 51678 |
---|---|
Other Names | MAGUK p55 subfamily member 6, Veli-associated MAGUK 1, VAM-1, MPP6, VAM1 |
Target/Specificity | This MPP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 360-388 amino acids from the Central region of human MPP6. |
Dilution | WB~~1:1000 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | MPP6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PALS2 (HGNC:18167) |
---|---|
Synonyms | MPP6, VAM1 |
Cellular Location | Membrane; Peripheral membrane protein |
Tissue Location | Abundant in testis, brain, and kidney with lower levels detectable in other tissues |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily.
References
Scheel,A.K., et.al., Ann. Rheum. Dis. 65 (5), 595-600 (2006)
Rush,J., et.al., Nat. Biotechnol. 23 (1), 94-101 (2005)
Rush,J., et.al., Nat. Biotechnol. 23 (1), 94-101 (2005)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.