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MGEA5 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, IP |
|---|---|
| Primary Accession | O60502 |
| Clonality | Monoclonal |
| Other Names | HEXC; MEA5; Mgea5; NCOAT; OGA; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 102915 Da |
| Dilution | WB 1:1000~1:5000 IHC 1:50~1:200 IP 1:80 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human MGEA5 |
| Description | Isoform 1: Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Isoform 3: Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | OGA {ECO:0000303|PubMed:20863279, ECO:0000312|HGNC:HGNC:7056} |
|---|---|
| Function | [Isoform 1]: Cleaves GlcNAc but not GalNAc from O- glycosylated proteins (PubMed:11148210, PubMed:11788610, PubMed:20673219, PubMed:22365600, PubMed:24088714, PubMed:28939839, PubMed:37962578). Deglycosylates a large and diverse number of proteins, such as CRYAB, ELK1, GSDMD, LMNB1 and TAB1 (PubMed:28939839, PubMed:37962578). Can use p-nitrophenyl-beta-GlcNAc and 4- methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta- GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro) (PubMed:20673219). Does not bind acetyl-CoA and does not have histone acetyltransferase activity (PubMed:24088714). |
| Cellular Location | [Isoform 3]: Nucleus |
| Tissue Location | Ubiquitous. Shows highest expression in the brain, placenta and pancreas. |
Research Areas
Citations (0)
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
$ 175.00
Cat# AP91971
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