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> home > Products > Primary Antibodies > Antibody Collections > Prostate positive > Nectin 2 Antibody
Nectin 2 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC, IP |
|---|---|
| Primary Accession | Q92692 |
| Reactivity | Rat |
| Clonality | Monoclonal |
| Other Names | HVEB; PRR2; CD112; PVRR2; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 57742 Da |
| Dilution | WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:100 FC 1:50 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human Nectin 2 |
| Description | Probable cell adhesion protein. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | NECTIN2 (HGNC:9707) |
|---|---|
| Synonyms | HVEB, PRR2, PVRL2 |
| Function | Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive (PubMed:26755705). Probable cell adhesion protein (PubMed:9657005). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Ubiquitous. |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
$ 175.00
Cat# AP91953
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