COMT Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
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Primary Accession | P21964 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | Catechol O methyltransferase; COMT; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 30037 Da |
Dilution | WB 1:500~1:2000 IHC 1:50~1:200 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human COMT |
Description | Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | COMT (HGNC:2228) |
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Function | Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol. |
Cellular Location | [Isoform Soluble]: Cytoplasm |
Tissue Location | Brain, liver, placenta, lymphocytes and erythrocytes |
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