Cdx1 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, ICC |
---|---|
Primary Accession | P47902 |
Clonality | Monoclonal |
Other Names | CDX1; Homeobox protein CDX 1; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 28138 Da |
Dilution | WB 1:500~1:1000 ICC/IF 1:50~1:200 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human Cdx1 |
Description | Could play a role in the terminal differentiation of the intestine. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | CDX1 |
---|---|
Function | Plays a role in transcriptional regulation (PubMed:24623306). Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the PRKD1 promoter in colorectal cancer (CRC) cells (PubMed:24623306). Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA (PubMed:28473536). |
Cellular Location | Nucleus. |
Tissue Location | Intestinal epithelium. |
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