Nucleostemin Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, FC, ICC |
---|---|
Primary Accession | Q9BVP2 |
Clonality | Monoclonal |
Other Names | E2IG3; GNL3; NNP47; NS; Nucleostemin; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 61993 Da |
Dilution | WB 1:500~1:2000 ICC/IF 1:50~1:200 FC 1:50 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human Nucleostemin |
Description | May be required to maintain the proliferative capacity of stem cells and may play an important role in tumorigenesis. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | GNL3 |
---|---|
Synonyms | E2IG3, NS |
Function | May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity). |
Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q811S9}. Nucleus, nucleolus. Note=Shuttles between the nucleus and nucleolus. {ECO:0000250|UniProtKB:Q811S9} |
Tissue Location | Increased levels in lung tissue in cancer patients. |
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