Thioredoxin 2 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC, ICC |
---|---|
Primary Accession | Q99757 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | MT-TRX; MTRX; Thioredoxin2; TRX2; TXN2; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 18383 Da |
Dilution | WB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:100 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human Thioredoxin 2 |
Description | Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | TXN2 |
---|---|
Synonyms | TRX2 |
Function | Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity. |
Cellular Location | Mitochondrion |
Tissue Location | Widely expressed in adult (at protein level) and fetal tissues. |
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