Mast Cell Chymase Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
---|---|
Primary Accession | P23946 |
Clonality | Monoclonal |
Other Names | Chymase 1; Chymase; CMA1; CYH; CYM; Mcp-5; MCP3P; Mcpt5; MCT1; MMCP-5; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 27325 Da |
Dilution | WB 1:1000~1:5000 IHC 1:50~1:200 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human Mast Cell Chymase |
Description | Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | CMA1 |
---|---|
Synonyms | CYH, CYM |
Function | Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. |
Cellular Location | Secreted. Cytoplasmic granule. Note=Mast cell granules |
Tissue Location | Mast cells in lung, heart, skin and placenta. Expressed in both normal skin and in urticaria pigmentosa lesions |
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