PFDN5 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, IP |
---|---|
Primary Accession | Q99471 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | EIG 1; Eig1; MM1; PFD5; PFDN5; Prefoldin 5; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 17328 Da |
Dilution | WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human PFDN5 |
Description | Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | PFDN5 |
---|---|
Synonyms | MM1, PFD5 |
Function | Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC. |
Cellular Location | [Isoform 1]: Nucleus. [Isoform 3]: Nucleus. |
Tissue Location | Highly expressed in pancreas and skeletal muscle and moderately in other tissues |
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