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CD23 Antibody

Rabbit mAb

     
  •  - CD23 Antibody AP91614
    Western blot analysis of CD23 expression in Raji cell lysate.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC, FC
Primary Accession P06734
Clonality Monoclonal
Other Names CD23; FCE2; CD23A; IGEBF; CLEC4J; FCER2;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 36469 Da
Additional Information
Dilution WB 1:500~1:1000 IHC 1:50~1:200 FC 1:30
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human CD23
Description This receptor has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name FCER2
Synonyms CD23A, CLEC4J, FCE2, IGEBF
Function Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells (PubMed:2167225). On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine- nitric oxide pathway (PubMed:7544003).
Cellular Location Cell membrane; Single-pass type II membrane protein. Cell membrane; Lipid-anchor. Secreted. Note=Also exists as a soluble excreted form, sCD23
Tissue Location Detected in urine (at protein level).
Research Areas
Citations (0)
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$ 350.00
$ 175.00
Cat# AP91614
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