ETS1 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, FC |
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Primary Accession | P14921 |
Clonality | Monoclonal |
Other Names | C ets 1 protein; ETS 1; ETS1; ETS1 oncogene; EWSR2; Oncogene ETS1; P54; Protein C-ets-1; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 50408 Da |
Dilution | WB 1:500~1:2000 FC 1:80 |
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Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human ETS1 |
Description | Transcription factor. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | ETS1 |
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Synonyms | EWSR2 |
Function | Transcription factor (PubMed:10698492, PubMed:11909962). Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts (PubMed:20378371). May control the differentiation, survival and proliferation of lymphoid cells (PubMed:20378371). May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion (PubMed:15247905, PubMed:15592518). |
Cellular Location | Nucleus. Cytoplasm Note=Delocalizes from nucleus to cytoplasm when coexpressed with isoform Ets-1 p27. |
Tissue Location | Highly expressed within lymphoid cells. Isoforms c- ETS-1A and Ets-1 p27 are both detected in all fetal tissues tested, but vary with tissue type in adult tissues. None is detected in brain or kidney. |
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