CD42b Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
---|---|
Primary Accession | P07359 |
Clonality | Monoclonal |
Other Names | Antigen CD42b alpha; BDPLT1; BDPLT3; BSS; CD42b alpha; DBPLT3; Glycoprotein Ibalpha; GP Ib alpha; GP1B; GP1BA; GPIb alpha; GPIbA; VWDP; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 71540 Da |
Dilution | WB 1:1000~1:5000 IHC 1:50~1:200 |
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Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human CD42b |
Description | CD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. Its expression and activation seems to be regulated by VEGF and PDGF. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | GP1BA |
---|---|
Function | GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium. |
Cellular Location | Membrane; Single-pass type I membrane protein. |
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