KLKB1 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, IP |
---|---|
Primary Accession | P03952 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | Fletcher factor; kallikrein B plasma; Kallikrein B1; Kininogenin; KLK3; KLKB1; PKK; PKKD; Plasma kallikrein light chain; PPK; Prekallikrein; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 71370 Da |
Dilution | WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human KLKB1 |
Description | The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | KLKB1 |
---|---|
Synonyms | KLK3 |
Function | Participates in the surface-dependent activation of blood coagulation. Activates, in a reciprocal reaction, coagulation factor XII/F12 after binding to negatively charged surfaces. Releases bradykinin from HMW kininogen and may also play a role in the renin- angiotensin system by converting prorenin into renin. |
Cellular Location | Secreted. |
Tissue Location | Found in plasma (at protein level). |
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