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Ferritin Light Chain Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, IP |
|---|---|
| Primary Accession | P02792 |
| Reactivity | Rat |
| Clonality | Monoclonal |
| Other Names | Ferritin L chain; Ferritin L subunit; Ferritin light chain; Ferritin light polypeptide; ferritin light polypeptide like 3; FTL; LFTD; NBIA 3; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 20020 Da |
| Dilution | WB 1:1000~1:5000 IP 1:50 FC 1:100 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human Ferritin Light Chain |
| Description | Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | FTL |
|---|---|
| Function | Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). Delivery to lysosomes by the cargo receptor NCOA4 for autophagic degradation and release or iron (PubMed:24695223). |
| Cellular Location | Cytoplasmic vesicle, autophagosome. Cytoplasm {ECO:0000250|UniProtKB:P29391}. Autolysosome {ECO:0000250|UniProtKB:P29391} |
Research Areas
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Application Protocols
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$ 350.00
$ 175.00
Cat# AP91385
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