GLUT3 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P11169 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | brain; Glucose transporter type 3; GLUT3; Slc2a3; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 53924 Da |
Dilution | WB 1:500~1:2000 |
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Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human GLUT3 |
Description | Facilitative glucose transporter. Probably a neuronal glucose transporter. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | SLC2A3 (HGNC:11007) |
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Function | Facilitative glucose transporter (PubMed:26176916, PubMed:32860739, PubMed:9477959). Can also mediate the uptake of various other monosaccharides across the cell membrane (PubMed:26176916, PubMed:9477959). Mediates the uptake of glucose, 2- deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate (PubMed:26176916, PubMed:9477959). Does not mediate fructose transport (PubMed:26176916, PubMed:9477959). Required for mesendoderm differentiation (By similarity). |
Cellular Location | Cell membrane; Multi-pass membrane protein. Perikaryon {ECO:0000250|UniProtKB:Q07647}. Cell projection {ECO:0000250|UniProtKB:Q07647}. Note=Localized to densely spaced patches along neuronal processes. {ECO:0000250|UniProtKB:Q07647} |
Tissue Location | Highly expressed in brain (PubMed:8457197). Expressed in many tissues. |
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