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TBR1 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q16650 |
| Reactivity | Rat |
| Clonality | Monoclonal |
| Other Names | T box brain 1; T-brain-1; TBR 1; Tbr1; TES 56; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 74053 Da |
| Dilution | WB 1:500~1:2000 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human TBR1 |
| Description | Probable transcriptional regulator involved in developmental processes. Required for normal brain development. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | TBR1 |
|---|---|
| Function | Transcriptional repressor involved in multiple aspects of cortical development, including neuronal migration, laminar and areal identity, and axonal projection (PubMed:25232744, PubMed:30250039). As transcriptional repressor of FEZF2, it blocks the formation of the corticospinal (CS) tract from layer 6 projection neurons, thereby restricting the origin of CS axons specifically to layer 5 neurons (By similarity). |
| Cellular Location | Nucleus |
| Tissue Location | Brain. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
$ 175.00
Cat# AP91091
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