NEFH Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
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Primary Accession | P12036 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | NF-H; 200 kDa neurofilament protein; Neurofilament triplet H protein; KIAA0845; NFH; NEFH; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 112479 Da |
Dilution | WB 1:500~1:2000 IHC 1:100~1:500 |
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Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human NEFH |
Description | Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | NEFH |
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Synonyms | KIAA0845, NFH |
Function | Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. NEFH has an important function in mature axons that is not subserved by the two smaller NF proteins. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity). |
Cellular Location | Cytoplasm, cytoskeleton. Cell projection, axon {ECO:0000250|UniProtKB:P19246} |
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