MRC1 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, ICC |
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Primary Accession | P22897 |
Clonality | Monoclonal |
Other Names | Macrophage mannose receptor 1; MMR; CD206 antigen; MRC1; Mannose receptor C type 1; MRC1; CD206; CLEC13D; CLEC13DL; MRC1L1; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 166012 Da |
Dilution | WB 1:500~1:2000 ICC/IF 1:50~1:200 |
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Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human MRC1 |
Description | Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.(Microbial infection) Acts as phagocytic receptor for bacteria, fungi and other pathogens. Acts as a receptor for Dengue virus envelope protein E (PubMed:18266465). Interacts with hepatitis B virus envelope protein (PubMed:19683778). |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | MRC1 |
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Synonyms | CLEC13D, CLEC13DL, MRC1L1 |
Function | Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. (Microbial infection) Acts as a receptor for Dengue virus envelope protein E. |
Cellular Location | Endosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein |
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