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mGluR2 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, ICC |
|---|---|
| Primary Accession | Q14416 |
| Reactivity | Rat |
| Clonality | Monoclonal |
| Other Names | GRM2; Glutamate receptor homolog; GPRC1B; MGlu2; Metabotropic; GLUR2; MGLUR2; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 95568 Da |
| Dilution | WB 1:5000~1:10000 IHC 1:50~1:200 ICC/IF 1:50~1:200 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human mGluR2 |
| Description | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | GRM2 (HGNC:4594) |
|---|---|
| Synonyms | GPRC1B, MGLUR2 |
| Function | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Synapse. Cell projection, dendrite |
| Tissue Location | Detected in brain cortex (at protein level). Widely expressed in different regions of the adult brain as well as in fetal brain. |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
$ 175.00
Cat# AP90996
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