CDC40 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC, ICC |
---|---|
Primary Accession | O60508 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | cell division cycle 40; EH-binding protein 3; EHB3; pre-mRNA splicing factor 17; PRP17; PRPF17; Cdc40; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 65521 Da |
Dilution | WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human CDC40 |
Description | Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | CDC40 |
---|---|
Synonyms | EHB3, PRP17, PRPF17 |
Function | Required for pre-mRNA splicing as component of the activated spliceosome (PubMed:33220177). Plays an important role in embryonic brain development; this function does not require proline isomerization (PubMed:33220177). |
Cellular Location | Nucleus. Nucleus speckle |
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