HDAC9 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, ICC, IP |
---|---|
Primary Accession | Q9UKV0 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | HD9; Histone deacetylase 7B; HD7; HD7b; Histone deacetylase-related protein; HDAC9; HDAC7; HDAC7B; HDRP; MITR; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 111297 Da |
Dilution | WB 1:5000~1:20000 IHC 1:50~1:200 ICC/IF 1:50~1:200 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human HDAC9 |
Description | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | HDAC9 |
---|---|
Synonyms | HDAC7, HDAC7B, HDRP, KIAA0744, MITR |
Function | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription. |
Cellular Location | Nucleus. |
Tissue Location | Broadly expressed, with highest levels in brain, heart, muscle and testis. Isoform 3 is present in human bladder carcinoma cells (at protein level). |
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