Angiotensinogen Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, ICC, IP |
---|---|
Primary Accession | P01019 |
Clonality | Monoclonal |
Other Names | Angiotensinogen; Serpin A8; AGT; SERPINA8; Des-Asp[1]-angiotensin II; Serine (or cysteine) proteinase inhibitor; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 53154 Da |
Dilution | WB 1:1000~1:2000 ICC/IF 1:50~1:200 IP 1:50 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human Angiotensinogen |
Description | Angiotensin is formed from a precursor, angiotensinogen, which is produced by the liver and found in the a-globulin fraction of plasma. Angiotensin stimulation through AT1 has been shown to activate the JAK/Stat pathway involving a direct interaction between JAK2 and AT1 as demonstrated by co-immunoprecipitation. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | AGT (HGNC:333) |
---|---|
Synonyms | SERPINA8 |
Function | Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. |
Cellular Location | Secreted |
Tissue Location | Expressed by the liver and secreted in plasma. |
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