Cytochrome C Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC, ICC, IP |
---|---|
Primary Accession | P99999 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | CYC; CYCS; Cytochrome c; HCS; THC4; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 11749 Da |
Dilution | WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:30 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human Cytochrome C |
Description | Cytochrome C is a well conserved electron-transport protein and is part of the respiratory chain localized to mitochondrial intermembrane space. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome C into the cytosol. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | CYCS |
---|---|
Synonyms | CYC |
Function | Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. |
Cellular Location | Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane |

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