MSI2 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC, ICC |
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Primary Accession | Q96DH6 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | MSI2H; MGC3245; MSI2; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 35197 Da |
Dilution | WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:30 |
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Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human MSI2 |
Description | Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | MSI2 |
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Function | RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity). |
Cellular Location | Cytoplasm. Note=Associated with polysomes. |
Tissue Location | Ubiquitous; detected at low levels. |
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