PI 3 Kinase p55 gamma Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, ICC |
---|---|
Primary Accession | Q92569 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | GRB1, P85A, PI3-kinase p85-alpha subunit, PI3K, PI3K p85-alpha; P55G, PI3-kinase p85-gamma subunit, PI3K p85-gamma, |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 54448 Da |
Dilution | WB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:50~1:200 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human PI 3 Kinase p55 gamma |
Description | Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. Highest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | PIK3R3 |
---|---|
Function | Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. |
Tissue Location | Highest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle |
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