GFAP Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, ICC, IP |
---|---|
Primary Accession | P14136 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | GFAP; FLJ45472; gfapl; ALXDRD; CB345; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 49880 Da |
Dilution | WB 1:10000~1:50000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:30 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human GFAP |
Description | GFAP is commonly used as a marker for intracranial and intraspinal tumors arising from astrocytes. In addition, GFAP intermediate filaments are also present in nonmyelin-forming Schwann cells in the peripheral nervous system |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | GFAP |
---|---|
Function | GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. |
Cellular Location | Cytoplasm. Note=Associated with intermediate filaments |
Tissue Location | Expressed in cells lacking fibronectin. |
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