Ras Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, FC, IP |
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Primary Accession | P01111 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | GTPase HRas;GTPase KRas;GTPase NRas;H-Ras-1;HAMSV;HRAS;HRAS1;K-RAS;N-RAS;NRAS;p21ras;RASH1;RASK2;Transforming protein p21 |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 21229 Da |
Dilution | WB 1:10000~1:20000 IP 1:20 FC 1:50 |
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Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human Ras |
Description | HRas a small GTPase protein of the Ras family. Alternates between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase-activating protein (GAP). Mutations are implicated in a variety of human tumors. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | NRAS |
---|---|
Synonyms | HRAS1 |
Function | Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. |
Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor Note=Shuttles between the plasma membrane and the Golgi apparatus |
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