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CARD6 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q9BX69 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 116468 Da |
| Antigen Region | 755-787 aa |
| Gene ID | 84674 |
|---|---|
| Other Names | Caspase recruitment domain-containing protein 6, CARD6 |
| Target/Specificity | This CARD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human CARD6. |
| Dilution | WB~~1:1000 IHC-P~~1:25 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CARD6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CARD6 |
|---|---|
| Function | May be involved in apoptosis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
CARD6 is a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB.
References
Kim,S.S., et.al., Pathology 42 (1), 50-53 (2010)
Olsen,J.V., et.al., Cell 127 (3), 635-648 (2006)
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