Lactate Dehydrogenase Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC, ICC, IP |
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Primary Accession | P00338 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | LDHA; LDH-M; LDH1; PIG19; GSD11; TRG5; Proliferation inducing gene 19; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 36689 Da |
Dilution | WB 1:500~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:100 IP 1:50 FC 1:50 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human Lactate Dehydrogenase |
Description | Lactate dehydrogenase (LDH) catalyzes the interconversion of pyruvate and NADH to lactate and NAD+. When the oxygen supply is too low for mitochondrial ATP production, this reaction recycles NADH generated in glycolysis to NAD+, which reenters glycolysis. The major form of LDH found in muscle cells is the A (LDHA) isozyme. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | LDHA (HGNC:6535) |
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Function | Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+). |
Cellular Location | Cytoplasm. |
Tissue Location | Predominantly expressed in anaerobic tissues such as skeletal muscle and liver. |
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