MMP1 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC, ICC |
---|---|
Primary Accession | P03956 |
Clonality | Monoclonal |
Other Names | MMP1;CLG;CLGN; Fibroblast collagenase; Matrix metalloprotease 1; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 54007 Da |
Dilution | WB 1:500~1:2000 IHC 1:50~1:200 ICC 1:50~1:200 FC 1:50 |
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Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human MMP1 |
Description | MMP1 Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity. Belongs to the peptidase M10A family. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | MMP1 |
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Synonyms | CLG |
Function | Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X (PubMed:1645757, PubMed:2153297, PubMed:2557822). In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity (PubMed:16807369). |
Cellular Location | Secreted, extracellular space, extracellular matrix |
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