CETP Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IP |
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Primary Accession | P11597 |
Clonality | Monoclonal |
Other Names | BPIFF; HDLCQ10;CETP; Lipid transfer protein I; Cholesteryl ester transfer protein; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 54756 Da |
Dilution | WB 1:500~1:2000 IP 1:50 |
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Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human CETP |
Description | Cholesteryl ester transfer protein (CETP) is a circulating metabolic enzyme that transports cholesterol from the arteries to the liver. CETP converts cholesteryl esters from antiatherogenic high density lipoproteins (HDLs) to proatherogenicapolipoprotein B (apoB)-containing lipoproteins, including very low-, intermediate-, and low-DLs. Efficient transfer and exchange of cholesteryl esters and triglycerides between the lipoprotein classes of human plasma is necessary to maintain healthy arteries. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | CETP (HGNC:1869) |
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Function | Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL (PubMed:24293641, PubMed:3281933, PubMed:3600759). Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (PubMed:17237796). |
Cellular Location | Secreted. Note=Secreted in plasma |
Tissue Location | Expressed by the liver and secreted in plasma. |
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