Phospho-alpha Tubulin (Y272) Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, ICC |
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Primary Accession | P68363 |
Reactivity | Human |
Clonality | Monoclonal |
Other Names | Alpha-tubulin 3; B-ALPHA-1; FLJ25113; hum-a-tub1; hum-a-tub2; LIS3; TBA1A; TUBA1A; TUBA3; Tubulin alpha-1A chain; Tubulin alpha-3 chain; Tubulin B-alpha-1; tubulin, alpha 1a; tubulin, alpha 3; tubulin, alpha, brain-specific |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 50152 Da |
Dilution | WB 1:500~1:2000 ICC/IF 1:50~1:200 |
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Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human Phospho-alpha Tubulin (Y272) |
Description | TUBA1A Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | TUBA1B |
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Function | Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:34996871). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms (PubMed:34996871). Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha- tubulin (PubMed:34996871). |
Cellular Location | Cytoplasm, cytoskeleton |
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