alpha smooth muscle Actin Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC, IP |
---|---|
Primary Accession | P62736 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | Actin, aortic smooth muscle; Alpha-actin-2; ACTA2; ACTSA; ACTVS; GIG46; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 42009 Da |
Dilution | WB 1:500~1:2000 IHC 1:50~1:200 IP 1:30 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human alpha smooth muscle Actin |
Description | Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. AATs are characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | ACTA2 |
---|---|
Synonyms | ACTSA, ACTVS |
Function | Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. |
Cellular Location | Cytoplasm, cytoskeleton. |
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