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alpha smooth muscle Actin Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, FC, ICC |
|---|---|
| Primary Accession | P62736 |
| Reactivity | Rat |
| Clonality | Monoclonal |
| Other Names | Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, ACTA2, ACTSA, ACTVS, GIG46 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 42009 Da |
| Dilution | WB 1:1000~1:10000 IHC 1:500~1:1000 ICC/IF 1:100~1:500 FC 1:20 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human alpha smooth muscle Actin |
| Description | Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | ACTA2 |
|---|---|
| Synonyms | ACTSA, ACTVS |
| Function | Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. |
| Cellular Location | Cytoplasm, cytoskeleton. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
$ 175.00
Cat# AP90063
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