beta I Tubulin Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC, ICC |
---|---|
Primary Accession | Q9H4B7 |
Reactivity | Rat, Dog |
Clonality | Monoclonal |
Other Names | Beta tubulin 1, class VI;Class VI beta tubulin antibody;TBB1_HUMAN;TUBB1;Tubulin beta 1 class VI;Tubulin, beta 1 antibody |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 50327 Da |
Dilution | WB 1:3000~1:10000 IHC 1:100~1:200 ICC/IF 1:100~1:200 FC 1:100 |
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Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human beta I Tubulin |
Description | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | TUBB1 |
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Function | Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. |
Cellular Location | Cytoplasm, cytoskeleton |
Tissue Location | Hematopoietic cell-specific. Major isotype in leukocytes, where it represents 50% of all beta-tubulins |
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