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FNDC5 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 3
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, E |
|---|---|
| Primary Accession | Q8NAU1 |
| Other Accession | Q8K3V5, Q8K4Z2, Q1L867 |
| Reactivity | Human |
| Predicted | Zebrafish, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 28283 Da |
| Antigen Region | 159-185 aa |
| Gene ID | 252995 |
|---|---|
| Other Names | Fibronectin type III domain-containing protein 5, Fibronectin type III repeat-containing protein 2, Irisin, FNDC5, FRCP2 |
| Target/Specificity | This FNDC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-185 amino acids from the C-terminal region of human FNDC5. |
| Dilution | WB~~1:1000 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FNDC5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FNDC5 |
|---|---|
| Synonyms | FRCP2 |
| Function | [Irisin]: Mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA. |
| Cellular Location | [Fibronectin type III domain-containing protein 5]: Cell membrane; Single-pass membrane protein. Peroxisome membrane {ECO:0000250|UniProtKB:Q8K4Z2}; Single-pass membrane protein. Note=Imported into peroxisomes through the PEX5 receptor pathway. {ECO:0000250|UniProtKB:Q8K4Z2} |
| Tissue Location | Widely expressed, with highest levels in heart. Very low expression, if any, in colon, pancreas and spleen |
Research Areas
Citations ( 0 )
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Teufel,A., et.al., Gene 297 (1-2), 79-83 (2002)
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$ 385.00
$ 150.00
Cat# AP8746b
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