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FNDC5 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - FNDC5 Antibody (C-term) AP8746b
    Western blot analysis of FNDC5 Antibody (C-term) (Cat. #AP8746b) in K562 cell line lysates (35ug/lane). FNDC5 (arrow) was detected using the purified Pab.
    detail
  • FC - FNDC5 Antibody (C-term) AP8746b
    FNDC5 Antibody (C-term) (Cat. #AP8746b) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
  • SPECIFICATION
  • CITATIONS: 3
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, FC, E
Primary Accession Q8NAU1
Other Accession Q8K3V5, Q8K4Z2, Q1L867
Reactivity Human
Predicted Zebrafish, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 23659 Da
Antigen Region 159-185 aa
Additional Information
Gene ID 252995
Other Names Fibronectin type III domain-containing protein 5, Fibronectin type III repeat-containing protein 2, Irisin, FNDC5, FRCP2
Target/Specificity This FNDC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-185 amino acids from the C-terminal region of human FNDC5.
Dilution WB~~1:1000
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFNDC5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FNDC5
Synonyms FRCP2
Function [Irisin]: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue.
Cellular Location Cell membrane; Single-pass type I membrane protein Peroxisome membrane; Single-pass type I membrane protein. Note=Imported in peroxisomes through the PEX5 receptor pathway.
Tissue Location Widely expressed, with highest levels in heart. Very low expression, if any, in colon, pancreas and spleen
Research Areas
Citations ( 0 )

References

Teufel,A., et.al., Gene 297 (1-2), 79-83 (2002)

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$ 365.00
$ 140.00
Cat# AP8746b
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