LRPAP1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application
| WB, FC, IHC-P, E |
---|---|
Primary Accession | P30533 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 41466 Da |
Antigen Region | 281-309 aa |
Gene ID | 4043 |
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Other Names | Alpha-2-macroglobulin receptor-associated protein, Alpha-2-MRAP, Low density lipoprotein receptor-related protein-associated protein 1, RAP, LRPAP1, A2MRAP |
Target/Specificity | This LRPAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-309 amino acids from the C-terminal region of human LRPAP1. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | LRPAP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | LRPAP1 (HGNC:6701) |
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Synonyms | A2MRAP |
Function | Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway. |
Cellular Location | Rough endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment lumen. Golgi apparatus, cis- Golgi network. Golgi apparatus lumen. Endosome lumen. Cell surface. Note=May be associated with receptors at the cell surface. |
Provided below are standard protocols that you may find useful for product applications.
Background
LRPAP1 interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330.
References
Lisi,S., et.al., J. Endocrinol. Invest. 30 (10), 839-843 (2007)
Vertegaal,A.C., et.al., Mol. Cell Proteomics 5 (12), 2298-2310 (2006)
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