Fatty Acid Synthase Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, FC, IP, ICC |
---|---|
Primary Accession | P49327 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 273427 Da |
Gene ID | 2194 |
---|---|
Other Names | FASN |
Dilution | WB~~1/500-1/1000 |
Format | Liquid |
Name | FASN |
---|---|
Synonyms | FAS |
Function | Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain. |
Cellular Location | Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV |
Tissue Location | Ubiquitous. Prominent expression in brain, lung, liver and mammary gland. |
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