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> home > Products > Primary Antibodies > Antibody Collections > Phospho Antibodies > Phospho-ErbB3 (Tyr1222) Rabbit mAb
Phospho-ErbB3 (Tyr1222) Rabbit mAb
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- BACKGROUND
Application 
| WB, IP, ICC |
|---|---|
| Primary Accession | P21860 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 148098 Da |
| Gene ID | 2065 |
|---|---|
| Other Names | ERBB3 |
| Dilution | WB~~1/500-1/1000 |
| Format | Liquid |
| Name | ERBB3 |
|---|---|
| Synonyms | HER3 |
| Function | Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778). May also be activated by CSPG5 (PubMed:15358134). Involved in the regulation of myeloid cell differentiation (PubMed:27416908). |
| Cellular Location | [Isoform 1]: Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Epithelial tissues and brain. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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