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Phospho-GATA3 (Ser308) Rabbit mAb

     
  • WB - Phospho-GATA3 (Ser308) Rabbit mAb AP78548
    detail
  • IHC - Phospho-GATA3 (Ser308) Rabbit mAb AP78548
    detail
  • SPECIFICATION
  • CITATIONS
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  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IP
Primary Accession P23771
Reactivity Human
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 47916 Da
Additional Information
Gene ID 2625
Other Names GATA3
Dilution WB~~1/500-1/1000
IHC~~1/50-1/100
Format Liquid
Protein Information
Name GATA3
Function Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression (By similarity). Coordinates macrophage transcriptional activation and UCP2-dependent metabolic reprogramming in response to IL33. Upon tissue injury, acts downstream of IL33 signaling to drive differentiation of inflammation-resolving alternatively activated macrophages.
Cellular Location Nucleus.
Tissue Location T-cells and endothelial cells.
Research Areas
Citations (0)
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$ 350.00
Cat# AP78548
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Ordering Information

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