PHOX2B Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, ICC |
---|---|
Primary Accession | Q99453 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 31621 Da |
Gene ID | 8929 |
---|---|
Other Names | PHOX2B |
Dilution | WB~~1/500-1/1000 |
Format | Liquid |
Name | PHOX2B |
---|---|
Synonyms | PMX2B |
Function | Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta- hydrolase and c-fos promoters, and of several enhancers including cAMP- response element and serum-response element. |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. |
Tissue Location | Expressed in neuroblastoma, brain and adrenal gland |
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