VARS Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P26640 |
Other Accession | Q04462, Q9Z1Q9 |
Reactivity | Human |
Predicted | Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 140476 Da |
Antigen Region | 679-707 aa |
Gene ID | 7407 |
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Other Names | Valine--tRNA ligase, Protein G7a, Valyl-tRNA synthetase, ValRS, VARS, G7A, VARS2 |
Target/Specificity | This VARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 679-707 amino acids from the Central region of human VARS. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | VARS Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | VARS1 (HGNC:12651) |
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Synonyms | G7A, VARS, VARS2 |
Function | Catalyzes the attachment of valine to tRNA(Val). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. This protein belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex.
References
Jiang,S., FEBS Lett. 579 (27), 6049-6054 (2005)
Bonnefond,L., Biochemistry 44 (12), 4805-4816 (2005)
Xie,T., Genome Res. 13 (12), 2621-2636 (2003)
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