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VARS Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | P26640 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 140476 Da |
| Antigen Region | 251-279 aa |
| Gene ID | 7407 |
|---|---|
| Other Names | Valine--tRNA ligase, Protein G7a, Valyl-tRNA synthetase, ValRS, VARS, G7A, VARS2 |
| Target/Specificity | This VARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-279 amino acids from the N-terminal region of human VARS. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | VARS Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | VARS1 (HGNC:12651) |
|---|---|
| Synonyms | G7A, VARS, VARS2 |
| Function | Catalyzes the attachment of valine to tRNA(Val). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. This protein belongs to the class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex.
References
Jiang,S., FEBS Lett. 579 (27), 6049-6054 (2005)
Bonnefond,L., Biochemistry 44 (12), 4805-4816 (2005)
Xie,T., Genome Res. 13 (12), 2621-2636 (2003)
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