ATAD2 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, FC, ICC |
---|---|
Primary Accession | Q6PL18 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 158554 Da |
Gene ID | 29028 |
---|---|
Other Names | ATAD2 |
Dilution | WB~~1/500-1/1000 |
Format | Liquid |
Name | ATAD2 |
---|---|
Function | May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells. |
Cellular Location | Nucleus |
Tissue Location | Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors. |
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