Gelsolin Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, FC, ICC |
---|---|
Primary Accession | P06396 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 85698 Da |
Gene ID | 2934 |
---|---|
Other Names | GSN |
Dilution | WB~~1/500-1/1000 |
Format | Liquid |
Name | GSN |
---|---|
Function | Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed (PubMed:19666512). Plays a role in ciliogenesis (PubMed:20393563). |
Cellular Location | [Isoform 2]: Cytoplasm, cytoskeleton. |
Tissue Location | Phagocytic cells, platelets, fibroblasts, nonmuscle cells, smooth and skeletal muscle cells |
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