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Iba1 Rabbit mAb
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- BACKGROUND
Application 
| WB, IHC-P, FC, ICC |
|---|---|
| Primary Accession | P55008 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 16703 Da |
| Gene ID | 199 |
|---|---|
| Other Names | AIF1 |
| Dilution | WB~~1/500-1/1000 |
| Format | Liquid |
| Name | AIF1 |
|---|---|
| Synonyms | G1, IBA1 |
| Function | Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. |
| Cellular Location | Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:O70200}. Cell projection, ruffle membrane {ECO:0000250|UniProtKB:O70200}; Peripheral membrane protein {ECO:0000250|UniProtKB:O70200}; Cytoplasmic side {ECO:0000250|UniProtKB:O70200}. Cell projection, phagocytic cup {ECO:0000250|UniProtKB:O70200}. Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis {ECO:0000250|UniProtKB:O70200} |
| Tissue Location | Detected in T-lymphocytes and peripheral blood mononuclear cells. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
Cat# AP77847
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