Antithrombin III Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, ICC |
---|---|
Primary Accession | P01008 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 52602 Da |
Gene ID | 462 |
---|---|
Other Names | SERPINC1 |
Dilution | WB~~1/500-1/1000 |
Format | Liquid |
Name | SERPINC1 |
---|---|
Synonyms | AT3 |
Function | Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade (PubMed:15140129, PubMed:15853774). AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa (PubMed:15140129). Its inhibitory activity is greatly enhanced in the presence of heparin. |
Cellular Location | Secreted, extracellular space. |
Tissue Location | Found in plasma. |
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