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Prothrombin Rabbit mAb

     
  • WB - Prothrombin Rabbit mAb AP77724
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IP
Primary Accession P00734
Reactivity Human
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 70037 Da
Additional Information
Gene ID 2147
Other Names F2
Dilution WB~~1/500-1/1000
Format Liquid
Protein Information
Name F2
Function Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Thrombin triggers the production of pro-inflammatory cytokines, such as MCP-1/CCL2 and IL8/CXCL8, in endothelial cells (PubMed:30568593, PubMed:9780208).
Cellular Location Secreted, extracellular space.
Tissue Location Expressed by the liver and secreted in plasma.
Research Areas
Citations (0)
citation

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$ 350.00
Cat# AP77724
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Ordering Information

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Shipping Information

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