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MEK2 Rabbit mAb
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- CITATIONS
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- BACKGROUND
Application 
| WB, IHC-P, FC, IP, ICC |
|---|---|
| Primary Accession | P36507 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 44424 Da |
| Gene ID | 5605 |
|---|---|
| Other Names | MAP2K2 |
| Dilution | WB~~1/500-1/1000 |
| Format | Liquid |
| Name | MAP2K2 |
|---|---|
| Synonyms | MEK2, MKK2, PRKMK2 |
| Function | Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity). Activates BRAF in a KSR1 or KSR2-dependent manner; by binding to KSR1 or KSR2 releases the inhibitory intramolecular interaction between KSR1 or KSR2 protein kinase and N-terminal domains which promotes KSR1 or KSR2-BRAF dimerization and BRAF activation (PubMed:29433126). |
| Cellular Location | Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane localization is probably regulated by its interaction with KSR1. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
Cat# AP77555
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